PhD - Hiring in process/Finished, not possible to apply

The lab

The work of the Glia-Immune Interactions lab is centered around the glia-lymphatic (glymphatic) system, which is a brain-wide clearance mechanism for solutes and proteins, and its role in CNS diseases. The glymphatic system is dependent on aquaporin 4 (AQP4) water channels located in astrocytes’ vascular endfeet for fluid influx and clearance. Disturbance of the glymphatic system in pathology and aging may increase the propensity for development of neurodegenerative diseases, or may aggravate pathology in neurodegenerative disease.

The goal of the lab is to obtain a deeper understanding of the glymphatic system including influx and efflux pathways for cerebrospinal fluid as well as its role in neurodegenerative diseases. This particular project will focus on Parkinson’s disease. The lab uses animal models of diseases and in vivo imaging to study the glymphatic system in health and disease. The lab is highly translational and uses models relevant to human diseases as well as patient samples to study diseases.

The principle investigator, Dr. Iben Lundgaard, is a recipient of a generous Wallenberg start up grant (15 million SEK). The lab is currently in the process of being set up at University of Lund. The Lundgaard lab has strong ties to collaboration partners at Lund, Copenhagen, and USA in order to conduct high impact experiments starting from day one.

The position

A fully funded Ph.D. position is available with start date June 1st (start date flexible). Salary and pension according to Swedish regulations are a very competitive package compared to other countries. This project will focus on investigation of the glymphatic system in physiology and models of neurodegenerative disease, particularly Parkinson’s disease.

Requirements

A M.Sc. degree in life science, medicine or similar is required.

Previous rodent work is required.

The candidate must have a minimum of 6 months experience with conducting full time lab research.

A strong interest in neuroscience, physiology and glia cells is required.

Mouse surgeries or colony management of transgenic mice a plus.

The successful candidates will have a strong drive for publishing articles and advancing science.

Candidates of all backgrounds are encouraged to apply.

 
Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Limit of tenure, four years according to HF 5 kap 7§.