Doktorand (PhD) in Bio Medicine and Stem Cell Biology - Hiring in process/Finished, not possible to apply

In the lab of Joan Yuan at the Division of Molecular Hematology, we are interested in the molecular basis for the developmental switch in hematopoietic output which results in a decreased rate of self-renewing cell divisions within the hematopoietic stem cell compartment as well as changes in the qualitative output in B cell subsets. Central to this developmental switch is the downregulation of the RNA-binding protein Lin28b. In this project, we aim to elucidate the molecular mechanisms by which Lin28b confers its fetal like effects on HSCs and control downstream cell fate choices.

Work duties
- Take part in the laboratory work and develop methods connected to the project
- Write articles and publications together with the supervisors
- Take part in everyday laboratory planning and meetings as well as participate in journal clubs and workshops, seminars and conferences
- Some administrative duties may occur
- Some teaching may occur
- Take part in the doctoral courses provided by the department and the faculty, and to independently find relevant literature to acquire knowledge in

Work with laboratory animals is included.

Qualifications
The applicant must be a highly ambitious scientist with great skills in reading and writing. The applicant should have knowledge and documented experience within the field of immunology and hematopoiesis in general and cellular barcoding in particular. Documented training and experience with laboratory animals and FACS is qualifying as well as prior experience in deep sequencing approaches.

Qualifying merits
A Master’s degree or likewise in Natural Science (Physical or Life Science) is a qualifying merit. International research experience is a plus. Previous documented knowledge and experience in stem cell biology is preferred.

Emphasis will be placed on personal suitability

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Limit of tenure, four years according to HF 5 kap 7§.