Institutionen för kliniska vetenskaper, Malmö

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 47 000 students and more than 8 800 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

The Lund University Diabetes Centre (LUDC; www.ludc.lu.se) opens a position for an Assistant Researcher. This is one of five positions now announced within the framework of the SSF funded project LUDC-IRC (www.ludc.lu.se/about-us/ludc-irc) and the strategic research environment Exodiab (https://www.exodiab.se/home/). LUDC is one of the largest diabetes research centres in the world with approximately 300 investigators and staff members working towards improved diagnosis, prevention and treatment of diabetes. The centre combines expertise in genetics, epidemiology, statistics, bioinformatics, molecular and cellular biology, physiology and clinical diabetes and endocrinology to achieve these goals. LUDC has large unique biobanks and databases with genome-wide data linked to national registries providing information on disease aetiology, progression as well as outcome and treatment. The centre has in-house platforms for most molecular genetic methods and metabolomics. Omics-information combined with extensive phenotyping allows a systems medicine approach to dissect the complexity of diabetes. A central theme of the Centre is to develop precision medicine to improve health and the quality of life of diabetic patients.

Work duties

The overall objective of this proposal is to identify and develop novel high-quality genetic and epigenetic biomarkers of clinical relevance that predict monitor progression and forecast response to treatment of T2D and CVD. The applicant will perform statistical and bioinformatics analyses of genome-wide human genetic and epigenetic data. He/she will also etablish optimal sub-cohorts for analyses of data by using databases. The applicant will also perform follow-up experiments regarding replication of generic and epigeneric results as well as by silencing and/or overexpression of candidate genes in cell lines. Data and results will be summarized and the postdoc will write manuscripts.

Qualifications

A PhD is a requirement. Good knowledge in type-2-diabetes, cardiovascular disease and epigenetic and genetic research. In particular, ability to perform pyrosequencing, cell culture, analysis of Illumina DNA methylation data and good knowledge in statistics and bioinformations of gemome-wide human data. Experience in analysis of metformin response is an advantage. Good knowledge in written and spoken English.

The university applies individual salary setting. Please indicate salary claims in your application.

Type of employment Temporary position
Contract type Full time
Number of positions 1
Full-time equivalent 100
City Malmö
County Skåne län
Country Sweden
Reference number PA2019/420
Contact
  • Charlotte Ling, +4640391213
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-222 93 62
  • SACO:Saco-s-rådet vid Lunds universitet, 046-222 93 64
Published 01.Feb.2019
Last application date 28.Mar.2019 11:59 PM CET

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