Assistant Researcher, department of infectious medicine, Lund - Hiring in process/Finished, not possible to apply

The Department of Clinical Sciences in Lund (IKVL) is one of six institutions at the Faculty of Medicine, Lund University. The department has a broad collaboration, both within the faculty and within other units at the University. IKVL also has a well-developed collaboration with Skåne University Hospital (SUS) and Region Skåne as well as the surrounding community and business. This is to promote clinical and experimental translational research, development and education.

The research group

The infection medicine proteomics lab (IMP) headed by Professor Johan Malmström develops quantitative and structural proteomics techniques to characterize the molecular mechanisms behind bacterial infections. The major goals include: 1) develop new structural proteomics techniques to investigate protein-protein interaction networks between host and pathogens 2) determine the properties characterizing a protective antibody response against bacterial pathogens and 3) determine biomarker panels associated with the onset of organ dysfunction in sepsis. The overall research vision is to provide improved understanding of the molecular interplay between host and pathogen at a systems-wide level that ultimately will lead to the development of new preventive, diagnostic and treatment opportunities for severe infections.

Within the research group, we ensure a good working environment with respect and consideration in our relationships with each other. We are constantly working to create the conditions for job satisfaction, development and participation for all employees.

We are hereby looking for an assistant researcher of 100 % with a starting date of 2020-08-15 (or by appointment) and end date 2022-08-14.

Work tasks

• Establish an Ig-rep-seq protocol with associated bioinformatics analysis
• Perform affinity- purification mass spectrometry analysis
• Develop a prototype proteogenomics workflow
• Perform multi-dimensional chromatography analysis of immune antibody mixtures.

Other existing tasks within the research group may also be relevant.

Qualifications

Requirements:

• PhD in proteomics, mass-spectrometry, systems biology or equivalent.
• Extensive experience in mass spectrometry analysis, including sample preparation, data acquisition and data analysis.
• Highly efficient in bioinformatics in particular coupled to mass spectrometry analysis.
• Previous experience in analyzing antibodies using mass spectrometry.
• Documented experience in MS analysis of protein complexes.
• Previous experience working with genomics analysis including sample preparation, data acquisition and data analysis.
• Extensive experience in multi-dimensional chromatography.

Great emphasis will be placed on personal suitability. The position require that you have good communication skills and that you are a team player. It also requires you to have the ability to work independently, having a high degree of self-motivation and that you are a good problem solver.

Highly desirable:

• Experience in working with human cells and bacteria.
• Experience in producing recombinant proteins.

Instructions for the application

The application must contain a personal letter describing how you fulfil the desired qualifications, a CV and diploma.

Other information

The university applies individual remuneration. Please indicate your salary claim in your application.