Postdoc in Molecular Hematology - Hiring in process/Finished, not possible to apply

The research group

The laboratory of RNA and Stem Cell Biology, led by associate senior lecturer Cristian Bellodi, is embedded within the Lund Stem Cell Center, an internationally ranked research center within the strategic areas of Stem Cell Biology and Regenerative Medicine at Lund University, Scandinavia’s largest institution for education and research. Our research focuses on new facets of gene expression control in stem and cancer cell at a molecular, cellular and organismal level. Specifically, we are interested in the molecular basis by which RNA modifications regulate gene expression in during development and in cancer.

Read more about our exciting research here.

Within the group we aim to maintain a good working environment based on mutual respect and consideration. We constantly strive to improve the conditions for work, development and participation for all employees.

The employment is a full time position, time limited to two years, regulated by central agreements regarding post-doctoral employments, with the desired access date on January 1st 2021, or according to agreement. 

Work assignments and area of expertise

The overarching goal of the project is to study the function of RNA modifying enzymes in stem and cancer cells. Our laboratory has recently discovered new roles for RNA pseudouridine modifications in control of small RNAs impacting protein synthesis and stem cell differentiation. The specific aims are: (1) characterize the molecular machinery responsible for biogenesis and function of stem cell- associated small RNAs, (2) unravel regulatory pathways governing specific RNA pseudouridine synthases in stem and cancer cells and (3) study the in vivo effects of altered RNA modifications.

Assessment criteria and other qualifications

This is a career development position primarily focused on research. The position is intended as an initial step in a career, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers.

Particular emphasis will be placed on research skills within the subject.

For appointments to a post-doctoral position, the ability to develop and conduct high quality research and also teaching skills will be evaluated as part of the assessment criteria.

Qualifications

Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree equivalent to a PhD, within a subject related to the position, completed no more than three years before the last date for applications. Under special circumstances, the doctoral degree can have been completed earlier.

Qualifications required:

• PhD in Biochemistry or equivalent
• Documented previous experience with protein production, RNA work (in vitro transcription, radiolabeling, EMSA, primer extension, northern blotting), standard molecular biology techniques (e.g. cloning, RT-qPCR, gel electrophoresis, western blotting), protein crystallography, mass spectrometry and cryo-electron microscopy
• Excellent verbal and written English communication skills 

Emphasis will be held at personal skills and suitability. The assignments require that you have the ability to work independently, have a good ability to work together and a good ability to communicate. Applicants must be able to work both independently and in groups.

Desirable skills:

• Expertise with macromolecular crystallization screening
• Experience of improving established models, protocols and/or developing new methods
• Certified qualification for laboratory animal science research in accordance to the EU legislation
• Documented experience of CRISPR/Cas9
• Documented previous work with lentivirala vectors

Terms of employment

This is a full-time, fixed-term employment of a maximum of 2 years. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term employment as a post-doctoral fellow”) between Lund University, SACO-S, OFR/S and SEKO, dated 4 September 2008.

Instructions for your application

The application must contain a personal letter describing how you fulfill the desired qualifications, a CV and diploma.

Other

The university applies individual salary setting. Please indicate your salary claim in your application.