Associate Researcher in Molecular Medicine and Gene Therapy - Hiring in process/Finished, not possible to apply

The Research Group

The research group for stem cells in myeloid neoplasms and bone marrow failure syndromes, led by senior lecturer Jörg Cammenga, is currently being started up and is now looking for an associate researcher for the exciting new research project. During the start-up of the new laboratory, the associate researcher will have a temporary workplace at the research group for Developmental Hematopoiesis. Take the chance to join us from the start and become a part of this innovative research!

The Developmental Hematopoiesis group is part of Lund Stem Cell Center, an internationally ranked research center within the strategic research area of stem cell biology and regenerative medicine at Lund University. In the laboratory, headed by David Bryder and Jörg Cammenga, we study both normal and malignant blood cell development from the perspectives of cell and molecular biology. Please read more about it here.

We strive for a good work environment where we show each other care and respect. A climate that is stimulating, developing and safe is important to us.

We are now looking for an associate researcher within the area of genomics, and in particular with the handling of various types of high throughput sequencing data generated in the laboratory. The position is a full time position time limited to 1 year starting September 1, 2021, or according to agreement.

Work duties and area of expertise

The work will mainly involve the study of the role of pattern recognition receptors in bone marrow failures and myeloid neoplasms. To achieve this goal the pathways downstream of the pattern recognition receptors will be studied using Western blotting, RNA sequencing and knock-down experiments using CRISPR/Cas9 methodology in primary human and murine hematopoietic cells both “in vitro” and “in vivo”.  

To show a biologically important link, animal (mouse) models of bone marrow failure and myeloid malignancies will be used and crossed with knock-out mice for specific pattern recognition receptors. Advanced flowcytometry will be used to study how different subpopulation in the hematopoietic hierarchy will be affected.  

The work will mainly involve informatics, although the candidate should also be able to acknowledge/comprehend the workflows involved in generating he data to be analyzed. 

Qualifications

The position requires:

• PhD in a relevant biomedical discipline
• Documented experience with research animal work
• Documented experience with advanced flow cytometry and molecular biology tools (including Crispr/Cas9)
• Documented experience and interest in medical science and an ability to plan and perform advanced experiments.
• Have the ability to supervise PhD and master students
• Very good oral and written communication skills in English

Great emphasis will be placed on personal suitability. You must have a good ability to work independently and have good planning, structural and prioritization skills. You must also have excellent communication and collaboration skills as we work closely within the research team. 

The following are merits for the position:

• Post-doctoral experience is desirable for this position

Instructions for your application

The application must contain a personal letter describing how you fulfill the desired qualifications, a CV and diploma.

Other

The university applies individual salary setting. Please indicate your salary claim in your application.