Lunds universitet, Medicinska fakulteten, Inst för laboratoriemedicin

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 47 000 students and more than 8 800 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

The Research Group

The laboratory of RNA and Stem Cell Biology is embedded within the Lund Stem Cell Center, an internationally ranked research center within the strategic areas of Stem Cell Biology and Regenerative Medicine at Lund University, Scandinavia’s largest institution for education and research. Our research focuses on new post-transcriptional facets of gene expression control in stem and cancer cell at a molecular, cellular and organismal level. Specifically, we are interested in the molecular basis by which RNA modifications regulate gene expression in during development and in cancer. Please read more about our research here. 

The research group has an open and welcomming work environment and we ensure that we take precautions to our physical as well as the organsiational and social work environment. 

We are now looking for a bioinformatician to proceed with the ongoing projects in the laboratory. The position is a permanent full time position starting September 6, 2021, or according to agreement.

Work duties and area of expertise

Successful applicant will be directly responsible for the bioinformatics analysis of the main ongoing projects in the laboratory that are centered on the role of RNA modifying enzymes in stem and cancer cells. Specifically, the applicant is expected to apply different bioinformatics pipelines to: (1) characterize novel molecular signatures of small RNAs in human and murine hematopoietic cells; (2) unravel regulatory pathways governing the biogenesis of small RNAs target of RNA modifying enzymes in stem and cancer cells and; (3) study the effects of altered RNA modifications for splicing and translation genome-wide.

Qualifications

The position requires:

  • PhD in Science within the field of Bioinformatics
  • Previous experience with analysis of a variety of high-throughput RNA sequencing (RNA-seq) datasets from mouse and human cells including whole transcriptome-seq, small RNA-seq, polysome-seq, ribosome footprint profile and iCLIP-seq
  • Good knowledge of pipelines for mRNA splicing analysis
  • Previous documented experience within academic groups interested in the research areas of RNA/cancer biology and hematology is needed
  • Excellent verbal and written English communication skills

Great emphasis will be placed on personal suitability. You must have great communication skills. You must also have great collaboration skills as well as be able to conduct your work independently and with high quality.

The following are merits for the position:

  • Previous experience with analysis of DNA and RNA epigenetics including WES, WGS, ChIP-seq, ATAC-seq, mRIP-seq, Nanopore RNA-seq and pseudo-seq

  • Relational database development and website integration knowledge

  • Research experience/knowledge in machine learning

  • Successful applicants should possess the capacity to improve established models, protocols and/or develops new methods

Instructions for your application

The application must contain a personal letter describing how you fulfill the desired qualifications, a CV and diploma.

Other

The university applies individual salary setting. Please indicate your salary claim in your application.

Type of employment Permanent position
Contract type Full time
Number of positions 1
Full-time equivalent 100
City Lund
County Skåne län
Country Sweden
Reference number PA2021/2684
Contact
  • Cristian Bellodi, rekryterande chef, +46462223054
  • Emelie Falck, personalsamordnare, 046-2220000
Published 23.Aug.2021
Last application date 05.Sep.2021 11:59 PM CEST

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