Project assistant in cell Reprogramming in Hematopoiesis and Immunity - Hiring in process/Finished, not possible to apply

Description of the workplace
The Cell Reprogramming in Hematopoiesis and Immunity group studies how hematopoietic cell fate is specified, maintained, and eventually modified or reversed. Inspired from the fields of stem cell biology, immunology, and cancer we use an interdisciplinary approach to mechanistically understand hematopoietic and immune cell identities and translate our findings into novel gene and cell therapies. The group focuses on cell reprogramming, hematopoiesis, and the development of cell and gene immunotherapeutic strategies. You can read more about our research here.

We are a diverse group of molecular biologists, MDs, PharmDs, tumor immunologists, stem cell biologists and computational scientists – at all career stages. At the Pereira lab, we view science as an opportunity to have fun exploring the unknown, while making unique contributions to society. Our multidisciplinary approach gets inspiration from the fields of immunology, developmental biology, stem cells, cancer biology and bioinformatics, cross-fertilizing ideas and leading to new discoveries. This requires diversity and teamwork both within the lab and with our worldwide academic and industrial collaborators. We view cooperation and communication as the formula for great science and success, both as team and as individuals. The Pereira lab provides an environment where creative and highly motivated minds can strive.

We are now looking for a higly motivated project assistant that will work on a project focusing on cancer cell reprogramming.

What we offer
Lund University is a public authority, which means that you will have special benefits, generous annual leave and an advantageous occupational pension. We also have a flexitime agreement that creates good conditions for work/life balance.

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Work duties and areas of responsibility

The aim is to develop complex cancer organoid models to 1) evaluate the reprogramming of cancer cells to dendritic cells in 3D culture systems, 2) evaluate the impact of the tumor immunosuppressive microenvironment in reprogramming efficiency and function and 3) to develop a predictive in vitro model for patient responses to reprogramming. The selected applicant will be responsible to lead a multifaceted approach including development of organoid models from patient-derived cancer cells, flow cytometry, immune function analysis, lentiviral production, etc. The successful candidate will also perform general laboratory organization and administration. 

Qualifications

• A MSc in Molecular Biology or related field
• Significant experience in cell culture and a BSL-2 laboratory setting
• Experience in lentivirus production
• Experience handling primary cancer cells and cancer organoids
• Experience with antigen presentation assays
• Experience in flow cytometry
• Ability to plan experiments, work independently in the lab, and keep an organized record
• Ability to communicate well with co-workers and to collaborate with other scientists.
• Excellent written and spoken English

Great importance will be attached to the compatibility of the applicant’s professional and personal disposition. We aim to find a candidate who is highly motivated, ambitious, collaborative, independent and well structured.

Additional qualifications for the position are:

• Experience with cellular reprogramming approaches, immunity, or hematopoeisis
• Attention to detail and time management skills are highly desired.
• Excellent problem-solving skills.

Further information
The position is permanent at 100 percent of full time and starting 2023-10-01 or according to agreement.

How to apply
Applications are to be submitted via the University’s recruitment system. The application is to/should include a personal letter justifying your interest in the position and how it matches your qualifications. The application is to/should also include a CV, degree certificates or equivalent and any other document to which you would like to draw attention (copies of grade transcripts, details of referees, letters of recommendation, etc.)