Lund University, Faculty of Medicine, Department of Laboratory Medicine, Lund

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 47 000 students and more than 8 800 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

Description of the workplace
The Cell Reprogramming in Hematopoiesis and Immunity research group at the Department of Laboratory Medicine within the Faculty of Medicine studies how hematopoietic cell fate is specified, maintained, and eventually modified or reversed.
The group focuses on cell reprogramming, hematopoiesis, and the development of cell and gene immunotherapeutic strategies. 
Inspired from the fields of stem cell biology, immunology, and cancer we use an interdisciplinary approach to mechanistically understand hematopoietic and immune cell identities and translate our findings into novel gene and cell therapies. You can read more about the research group at https://pereiralab.com/.
Our group is now recruiting a full-time PhD student that will work on the molecular mechanisms underlying DC reprogramming which will provide valuable information about the mode of action of TFs in reprogramming and cell lineage specification. Ultimately, this understanding could enable the generation of DCs with improved efficiency and fidelity and provide novel insights into the ontogeny of human DCs. 
The Cell Reprogramming in Hematopoiesis and Immunity research group is a diverse group of molecular biologists, MDs, PharmDs, tumor immunologists, stem cell biologists and computational scientists – at all career stages. Our multidisciplinary approach gets inspiration from the fields of immunology, developmental biology, stem cells, cancer biology and bioinformatics, cross-fertilizing ideas and leading to new discoveries. This requires diversity and teamwork both within the lab and with our worldwide academic and industrial collaborators.

We offer
Lund University is a public authority, which means that you will have special benefits, generous annual leave, and an advantageous occupational pension. We also have a flexitime agreement that creates good conditions for work/life balance.

Read more on the University website about being a Lund University employee
Work at Lund University

Work duties and areas of responsibility
The PhD student in this project will investigate how cooperative TF action is established and maintained, and to what extent it is required for cell fate conversion and development. The student will 1) examine TF interdependencies and interaction in DC reprogramming and 2) map TF cooperation changes over time, including genomic implications (e.g., histone mark redistribution, chromatin looping). Based on the generated multi-omics data, the student will 3) identify and validate molecular determinants of DC fate both in vitro and in vivo.

Qualifications
We are looking for you who have:

  •  the ability to work independently and the ability to collaborate well with other employees outside and within the research group
  • A strong drive and motivation.

Consideration will be given to how the applicant, through her or his experience and competence, is judged to have the ability needed to complete the doctoral program.
Great emphasis will be placed on personal characteristics

Requirements for employment are:

  • - A MSc degree in Biochemistry, biomedicine or similar.
  • - Knowledge on molecular cloning techniques.
  • - Knowledge on lentiviral particle generation.
  • - Experience with epigenomic data analysis.
  • - The ability to work independently in the laboratory.
  • - The ability to communicate well with co-workers and to collaborate with other scientists.
  • - Fluency in English.

Merits for the employment are:

  • Good knowledge of the cellular reprogramming or cancer immunotherapy fields
  • Experience in animal handling
  • Experience of independent work

Research expertise is the foremost criterion for employment. The evaluation of applicants will take account of their research profile, experience and knowledge.

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

Assessment basis
The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Further information
Temporary employment of four years, in accordance with the Higher Education Ordinance-
HF 5 kap 7§ in Sweden.
The employment is a full term position with the desired start date of 2024-01-01 or according to agreement. 

How to apply
You apply for the position via the University’s recruitment system. The application is to include a personal letter describing how you meet the qualification requirements and why you are interested in the position. The application is also to include a CV, degree certificates and any other documents to which you wish to draw attention (copies of, grade transcripts, details of referees, letters of recommendation, etc.)

 

 

 

 

Type of employment Temporary position
First day of employment 2024-01-01 or according to agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100
City Lund
County Skåne län
Country Sweden
Reference number PA2023/3101
Contact
  • Filipe Pereira, Recruting Manager, +46462224919,filipe.pereira@med.lu.se
  • Adam Niekrasz, HR-partner, +46462220000
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-2229362
  • SACO:Saco-s-rådet vid Lunds universitet, kansli@saco-s.lu.se
  • SEKO: Seko Civil, 046-2229366
Published 16.Nov.2023
Last application date 07.Dec.2023 11:59 PM CET

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