Doctoral student in Biology - Hiring in process/Finished, not possible to apply

Subject description

Biology is the broad subject about all living things. It encompasses everything from processes at the molecular and cellular level to global processes at ecosystem level. The subject is divided into a range of sub-disciplines and specialisations. The PhD programme at the Department of Biology includes many of these specialisations, from molecular biology to applied ecology, from viruses and individual cells to evolutionary biology and global biodiversity. Taking on research studies at the Department of Biology generally means focusing on a delimited part of the research area of biology and may include field studies, experiments, theoretical studies, or a combination of these.

Work duties

The main duties of doctoral students are to devote themselves to their research studies which includes participating in research projects and third cycle courses. The work duties can also include teaching and other departmental duties, up to 20%.

Oxygen-depleted environments, such as aquatic sediments, are widespread on our planet. While often considered "anoxic dead zones", these zones support diverse life, including eukaryotic microbes. These eukaryotes exhibit specialized metabolism especially in their mitochondria. The goal of this PhD project is to explore the mitochondrial biology of anaerobic eukaryotes to understand how their metabolism and organelle function has evolved in adaptation to environments without oxygen. We will focus on the anaerobic respiratory chain (electron transport chain) and other electron transferring strategies such as hydrogen generation. The student will investigate the functional diversity of anaerobic respiratory chains and the evolutionary mechanisms – such as lateral gene transfer - that have contributed to this adaptation.

The project will involve state-of-the-art cell biological methods such as super-resolution microscopy, proteomics and metabolomics of quinone molecules. There is also potential to develop strong comptence in bioinformatic methods such as transcriptomics, comparative genomics and phylogenetics.

The prospective doctoral candidate will join the Molecular Cell Biology Division in the Biology Department at Lund University under the supervision of Dr. Courtney Stairs who has a background in eukaryotic microbiology and co-supervised by Dr. Olivier van Aken a leading researcher in mitochondrial biology. This project is part of the European Research Council ‘TANGO2’ StG project awarded to Dr. Stairs.

Admission requirements

A person meets the general admission requirements for third-cycle courses and study programmes if he or she:

• has been awarded a second-cycle qualification, or
• has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second cycle, or
• has acquired substantially equivalent knowledge in some other way in Sweden or abroad.

A person meets the specific admission requirements for third cycle studies in Biology if he or she has passed an independent project (for example a degree project) of at least 30 credits in a relevant subject and have good oral and written proficiency in English.

Additional requirements

• A MSc in molecular biology/biochemistry/evolutionary biology or a closely related area. Candidates who are currently pursuing/completing their MSc are welcome to apply, provided that a degree certificate can be presented before admission/employment.
• Excellent oral and written proficiency in English.
• Demonstrated ability for proactive and independent work.
• Practical experience in molecular biology or cell biology of prokaryotic or eukaryotic microorganisms.

In addition to the mandatory requirements, documented experience in the following areas will be considered as strong merits:

• Investigations of non-model prokaryotic or eukaryotic microorganisms
• Experience with heterologous gene expression in yeast/prokaryotes or exploring yeast/prokaryotic physiology, anaerobic biology
• Experience with mitochondrial biochemistry or physiology

Assessment criteria

Selection for third-cycle studies is based on the student’s potential to profit from such studies. The assessment of potential is made primarily on the basis of academic results from the first and second cycle. Special attention is paid to the following:

• Knowledge and skills relevant to the thesis project and the subject of study.
• An assessment of ability to work independently and to formulate and tackle research problems.
• Written and oral communication skills
• Other experience relevant to the third-cycle studies, for example professional experience.

Consideration will also be given to strong collaborative skills, drive and independence, and how the applicant, through his or her experience and skills, is deemed to have the abilities necessary for successfully completing the third cycle programe.

Terms of employment

Only those admitted to third cycle studies may be appointed to a doctoral studentship. Third cycle studies consist of full-time studies for 4 years. A doctoral studentship is a fixed-term employment of a maximum of 5 years (including 20% departmental duties). Doctoral studentships are regulated in the Higher Education Ordinance (1993:100), chapter 5, 1–7 §§.

Instructions on how to apply

Applications shall be written in English and include a cover letter stating the reasons why you are interested in the postgraduate education programme and in what way the research project corresponds to your interests and educational background. The application must also contain a CV, degree certificate or equivalent, and other documents you wish to be considered (academic transcripts, publications).

Specific instructions for the CV:

• Maximum of two pages
• Degree information and MSc thesis title (if applicable)

Specific intructions for the cover letter:

• Maximum of two pages
• Include the contact information for 2-3 references
• Clearly motivate why you are interested in the project
• Include 1-2 sentences on a metabolic pathway you would like to learn more about as part of your thesis.