Assistant Researcher in Developmental Immunology

The workplace

The Research Group for Developmental Immunology conducts research on humoral immunity. We study how early immune exposure shapes B-cell memory and antibody production in the long term. The group is led by Associate Professor Joan Yuan and consists of PhD students, postdoctoral researchers, and technical staff. The group is located at the Biomedical Center in Lund, Department of Molecular Hematology. You can read more about our exciting research here. https://portal.research.lu.se/en/persons/joan-yuan

Within the research group, we value a good working environment with respect and care in our relationships with each other. We strive to create a workplace that is perceived as developing and stimulating for all employees. We continuously work to create conditions for job satisfaction, development, and participation for all employees.

We are hereby seeking a driven Assistant Researcher to work in neonatal B-cell immunology. The position is permanent and full-time, with a desired start date of January 1, 2025.

Worktasks and areas of responsiblity

As an Assistant Researcher, you will be responsible for working on studies regarding the role neonatal B-cells play in the creation of lifelong humoral immunity. The candidate should be an experienced, highly specialized, and independent researcher and is expected to drive the project and coordinate collaboration both within and outside the lab.

Your main tasks will include:

• Molecular biology methods such as cloning, PCR, and library generation for high-throughput sequencing
• Managing method development and troubleshooting with internal and external partners for new sequencing methods
• Coordination with internal and external partners for the development and maintenance of mouse colonies
• Bioinformatic analysis of VDJ sequencing
• Collaboration and coordination with lab members for the design and execution of sequencing experiments
• Development of new molecular methods

Qualifications

PhD and postdoctoral experience

Several years of experience as a research engineer Documented experience and training in flow cytometry Documented experience and training in bioinformatics, R studio Several years of experience in VDJ sequencing, scRNAseq, bulk RNAseq for low input samples.

Requirements

• Experience with Transnetyx genotyping service, as well as coordination with the animal facility in Lund

Experience with VDJseq analysis of B cell repertoires

Great emphasis will be placed on personal qualities. The tasks require that you can drive the project and solve problems independently, and coordinate with complex internal and external stakeholders.