PhD student in Molecular Skeletal Biology

Description of the workplace

The PhD project will be carried out within the Cell, Tissue and Organ Engineering Group led by Dr. Paul Bourgine. Bone is a complex organ that provides structural and mechanical support for our body, but also serves as our main hematopoietic center. The formation of bone involves different phases, including cartilage, vascularization, bone and bone marrow establishment. The Bourgine laboratory aims to gather human-specific knowledge about these processes, with a view to the development of innovative regenerative therapies. The research group is part of the Wallenberg Center for Molecular Medical Research and the Lund Stem Cell Center, at the Faculty of Medicine in Lund. More information is available on our website: www.bourginelab.com

The research group strives to conduct excellent research on an international level while maintaining a healthy working environment where everyone should feel involved, stimulated, and supported.

The Department of Clinical Sciences Lund is now announcing a vacancy for a PhD position and employment as a doctoral student within the research area Medical Science - ”Immuno-regulatory function of the human bone marrow niche”. The work will involve specific cell cultures and laboratory tasks with distinct associated techniques to understand the regulatory role of the bone marrow. The position is full-time for 48 months. The proposed starting date is March 1, 2025, or upon agreement.

We offer
Lund University is a public authority, which means that employees get benefits, generous annual leave and an advantageous occupational pension scheme. Read more on the University website about being a Lund University employee: Work at Lund University

Work description

The PhD student's main task is to conduct their own research project, and the work will be conducted within the PhD project "Immuno-regulatory function of the human bone marrow niche". The research group is funded by the Wallenberg Center for Molecular Medicine at Lund University (WCMM LU). The research group is focusing on regenerative medicine (regeneration, replacement and repair), and this is part of a national effort to positioning Sweden as a world-leading life science nation. Keywords are: Bone marrow tissue engineering, Engineering of bone marrow systems in vivo and Study of cellular crosstalk in 3D organoids. The results are expected to form the basis of a doctoral thesis.

Qualifications

Necessary qualifications for the job

• University degree (or equivalent foreign degree) in medicine, Genetics or biology
• Course in flow cytometry
• Course in animal experiments
• Course in confocal microscopy
• Experience in flow cytometry of immune populations
• Experience in Natural Killer and Dendritic cell biology
• Good knowledge of English (written and spoken)
• Experience in mesenchymal cell culture, construction of cartilage and bone tissue
• Experience in Cellular Reprogramming

Meritorious are:

• Education in Molecular and Cell Systems Biology
• Internationell erfarenhet och mobilitet

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad. The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Limit of tenure, four years according to HF 5 kap 7§.

How to apply
Applications are to be submitted via the University’s recruitment system. The application should include a CV and a personal letter justifying your interest in the position and how it matches your qualifications. The application should also include a degree certificate or equivalent and any other document to which you would like to draw attention (copies of grade transcripts, details of referees, letters of recommendation, etc.).

Welcome to apply!

The Department of Clinical Sciences Lund is one of six departments at the Faculty of Medicine. Clinical Sciences Lund cooperates closely with Skåne University Hospital and the Faculty of Medicine in order to optimize the conditions for preclinical and clinical translational research, research strategies and development, as well as education on both undergraduate and postgraduate levels.