Project Assistant in the Development of Cell-Based Immunotherapy - Hiring in process/Finished, not possible to apply

Description of the workplace
The research group is active within the Division of Clinical Genetics, which conducts world-leading cancer research with strong translational goals. The research primarily focuses on synthetic immunology, which includes strategies that rationally harness the immune system’s ability to perform complex functions. The goal is to improve cell-based immunotherapy for cancer, in which immune cells are programmed to locate and eliminate malignant cells. The research aims to develop new binding domains for synthetic receptors using generative AI, as well as to perform precise gene editing in immune cells to more specifically target cancer cells. These modified immune cells are studied using both in vitro and in vivo models. Analyses include, among other methods, multiparametric flow cytometry and high-resolution sequencing techniques.
The division has extensive collaboration between research groups and offers a broad range of cutting-edge expertise across different fields, as well as an open working environment.

What we offer
Lund University is a public authority, which means that you will have special benefits, generous annual leave and an advantageous occupational pension. We also have a flexitime agreement that creates good conditions forwork/life balance.
Read more on the University’s website about being a Lund University employee, Work at Lund University

Work duties and areas of responsibility
We are looking for a motivated, skilled, and ambitious employee with a high level of independence and flexibility in their role. You will work on isolating and programming primary immune cells with the aim of developing new powerful treatment strategies for difficult-to-treat cancer. To evaluate the therapeutic potential of these programmed immune cells, you will carry out a range of molecular and cell biology methods. The position therefore includes laboratory work such as tissue preparation and cell isolation, cloning, PCR, flow cytometry, ELISA, cell culture, and handling of primary human and murine samples. In addition, you will generate binding protein domains using established computational tools and evaluate them through protein structure prediction. Routine laboratory tasks are also part of the position.

Qualifications
Requirements for employment are:

• You have completed a Bachelor degree.
• You must be clearly independent and well-organized, with excellent collaboration skills.
• You must be capable of independently planning and conducting experimental studies and have the ability to flexibly solve and manage unforeseen challenges.
• You have experience with cell culture, molecular biology techniques (e.g., PCR techniques, DNA/RNA extraction), and flow cytometry (analysis and sorting).
• You have previously designed and performed exonuclease-based cloning (e.g., InFusion and Gibson).
• You have experience isolating and working with primary immune cells (such as T cells).
• You have practical experience performing precise genetic modifications in primary cells using the CRISPR/Cas9 system.
• You have experience developing binding domains using generative AI (e.g., diffusion- or hallucination-based tools).
• You have experience in structural biology and protein structure prediction (e.g., PyMOL, AlphaFold) is also required.

Additional qualifications for the position are:

• Knowledge in immunology, cell-based immunotherapy, and tumor biology is required.

Further information
This is a full-time fixed-term position (100%) for 12 months according to SÄVA with start from 2026-07-01 or according to agreement.

How to apply
You apply for the position via the University’s recruitment system. The application is to include a personal letter describing how you meet the qualification requirements and why you are interested in the position.
The application is also to include a CV and any other documents to which you wish to draw attention (copies of degree certificates, grade transcripts, details of referees, letters of recommendation, etc.)