Postdoc CoSAXS - Under tillsättning eller tillsatt, ej sökbar

The CoSAXS beamline is a state-of-the-art multipurpose Small Angle X-ray Scattering (SAXS) instrument at MAX IV which is currently under construction. It will offer high brilliance, monochromatic and tuneable X-rays, with outstanding performance in low beam divergence, high X-ray flux, and variable beam size in both directions in the full range of the sample-detector distances provided by the beamline (up to 18 m). Several techniques will be available through modular operation: time resolved SAXS, SAXS/WAXS, protein solution SAXS, microfocusing SAXS and XPCS. It is due to commence full user operation in 2019.

The CoSAXS beamline offers a postdoct position within the Röntgen-Ångström-Cluster funded project “Non-equilibrium thermodynamics of biology studied by time-resolved small-angle X-ray and neutron scattering”. This is a collaborative project between Gergely Katona, University of Gothenburg, Manfred Rössle, University of Lubeck, EMBL, PETRA III and FLASH at the Deutsches Elektronen-Synchrotron DESY, Hamburg, MAX IV Laboratory, Lund and the European Spallation Source ESS, Lund.

This project aims firstly to follow fast biochemical reactions at millisecond time scales. A laser-induced temperature jump will trigger the conversion of the biochemical species and the changes in protein function, for example, will be followed. A secondly goal of the research is to examine the non-thermal effects of terahertz radiation on such reactions. For both projects, we will use small angle X-ray scattering to follow the large scale structural dynamics of macromolecular complexes changes.

Tasks:

You will be responsible for the development of the fast triggering and synchronization of SAXS measurements with the laser or terahertz radiation source. You will work in collaboration with the CoSAXS team for the development of suitable sample environments for TT-SAS experiments. You will develop strategies for data collection, reduction and interpretation at the millisecond timescales.

You will present results at meetings, conferences and through publications. You will play an active role in experiments at other (international) facilities as part of the RÅC project, through proposal writing, experiment protocol planning, preparation of equipment, data collection and interpretation. You will share responsibilities for operation, maintenance and further development of the beamline in close collaboration with the CoSAXS team.

Qualifications:

-You must hold a PhD in physics, chemistry, materials science, electronics, engineering or a related discipline.
-You must have experience of (at least some of the following): the planning, design/construction/purchase, installation, operation and maintenance of complex scientific equipment.
-You should have experience in instrumentation controls hardware and software.

-You have a demonstrated ability to work independently.

-You have excellent command of spoken and written English, well-developed communication skills and team working skills.
-You must have experience of synchrotron-based SAXS experiments and data collection strategies.

The following qualifications are considered an asset:

- Experience of IR, terahertz or Raman spectroscopy in biophysics is an advantage.
- Experience of laser heating systems or terahertz radiation sources is considered an advantage.
- Experience of time-resolved measurements, including triggering and synchronization of data acquisition, is considered an advantage.
- Experience with molecular dynamics simulations is an advantage

This is a 2 year employment.

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