FragMAX postdoc - Hiring in process/Finished, not possible to apply

The FragMAX facility provides a user facility for crystallographic fragment screening at BioMAX, the first operational beamline for macromolecular crystallography at MAX IV. Our aim is to develop a platform which enables users with different levels of experience to routinely achieve actionable screening hits for their targets.

We are seeking to appoint a postdoctoral fellow (2-year appointment) for the FragMAX facility to further develop its current capabilities. This is an exciting opportunity for an aspiring post-doctoral fellow to join an international and interdisciplinary team, which is part of BioMAX and the MX-group. You will develop innovative screening protocols in order to facilitate and accelerate fragment elaboration. This will involve conceptual planning of suitable workflows, as well as testing and implementation of robust experimental protocols. Moreover, you will help to establish best practice data collection protocols for protein-ligand screening which make use of the unique capabilities of BioMAX. You will support users during fragment screening and other experiments and disseminate feedback in order to improve the overall performance of the facility. You are expected to work both independently and in close collaboration with the entire FragMAX and BioMAX teams, as well as with academic and industrial collaboration partners. A willingness to challenge existing paradigms and to explore new avenues would be an asset.

Work duties and areas of responsibility

• Development of innovative screening protocols in order to facilitate and accelerate fragment elaboration
• Establishment of best practice data collection protocols for protein-ligand screening
• User support at the FragMAX screening platform and continuous improvement of relevant processes
• Standard user support at BioMAX

Requirements

• PhD in a relevant area of structural biology, protein biochemistry or biophysics
• Demonstrated expertise in protein crystallography
• Demonstrated expertise in preparation and analysis of protein-ligand complexes
• Ability to work independently
• Ability to work as part of a team and to collaborate with a wide range of colleagues
• Very good command of spoken and written English

Desirable

• A record of publishing scientific papers
• Experience with fragment-based lead discovery
• Experience in computational chemistry

Other

• Participate in off-hour work
• Travel to international collaboration partners
• User support outside office hours