Doktorand (PhD) in Translational Cancer Research - Hiring in process/Finished, not possible to apply

The Division of Translational Cancer Research is starting up an exciting research project on anti-stromal therapy in pancreatic cancer in the group of Cancer and Matrix Remodelling. In this project we will examine the effect of anti-stromal therapy in different models of pancreatic cancer. More specifically, we believe that de-activation of cancer-associated fibroblasts will decrease tumour stiffness and improved tumour perfusion and drug uptake. Our group use advanced microscopy to understand metastatic progression and tissue remodelling i.e. using 2-photon microscopy, multispectral optoacoustic tomography and ultrasound. The PhD student will study how the physical and chemical properties of the tumour microenvironment affect cancer progression and how this can be perturbed to support chemotherapy treatment. The PhD student will work in a multidisciplinary, integrative approach to perform high quality translational research with collaborative partners world-wide.

Work duties
- Take part of the laboratory work connected to the project
- Method development for the project
- Work with animals is a requirement
- Write articles and publications together with the supervisors at the laboratory
- Participation in relevant seminars, workshops and conferences
- Some participation in the teaching of practical courses in the Research School and be involved in the teaching of master students in the lab
- Some administrative duties
- Take part of the doctoral courses provided by the Department and the Faculty

Work with experimental animals is included

Qualifications
The applicant must be a highly talented and highly ambitious scientist. The applicant should have knowledge and documented experience within the field of laboratory medicine in general and in cancer in particular. Documented training and experience with laboratory animals is qualifying as well as prior experience in basic cell biology. Qualifying is also knowledge and experience with fluorescence confocal microscopy.

Qualifying merits
A Master’s degree in Natural Science (Physical or Life Science) is a qualifying merit. Knowledge of the extracellular matrix and its composition, prior experience with cell culture work, transfection procedures and experience with virus work is also desirable. The applicant should also be fluent in English.

Emphasis will be placed on personal suitability

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Limit of tenure, four years according to HF 5 kap 7§.