PhD student in Biomedicine - Hiring in process/Finished, not possible to apply

The lung bioengineering and regeneration (LBR) group focuses on ex vivo modelling and molecular pathomechanisms of chronic lung diseases. A major interest of the group is to explore molecular mechanisms that contribute to the progression of idiopathic pulmonary fibrosis (IPF).

The LBR group is looking for a motivated doctoral candidate that will pursue the exploration of hippo pathway derangement in IPF. A suitable candidate will display the ability to work independently, to handle several projects simultaneously, and the ability to work well in a team in addition to familiarity and technical knowledge and experience with the Hippo pathway.

Work duties

The main objectives for the doctoral candidate will be to conduct research education, which includes participation in and development of research projects but also to master graduate courses and state-of-the-art techniques.

The aim of the project is to identify novel molecular mechanisms in the Hippo signalling pathway. Thus, the doctoral candidate will perform cell culture experiments including, but not limited to, cell isolation from mouse and human tissues, 2D cell culture, 3D organoid co-cultures, and 3D tissue cultures. The candidate will also perform basic laboratory techniques such as immunoblotting, immunoprecipitation, immunofluorescences and several types of gel electrophoresis. The candidate will also learn and perform mass spectrometry proteomics on their obtained samples.

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Requirements

A person meets the general admission requirements for third-cycle courses and study programs if he or she:

-has satisfied the requirements for courses comprising at least 240 credits of

which at least 60 credits were awarded in the second cycle, or

-has acquired substantially equivalent knowledge in some other way in Sweden or abroad.

Additional requirements:

For the present position, an undergraduate or master's degree is required from medical, biomedical, chemistry /

biology, bioengineering or other relevant natural science or engineering education.

Documented experience of laboratory work such as primary cell isolation, cell culture, tissue slicing techniques, animal work, cell and molecular biology techniques and advanced imaging methods and analysis.

Familiarity with the Hippo pathway and YAP/TAZ signaling is advantageous.

Merits

Ability to work independently as assessed from undergraduate or master thesis experiments or discussion of

science during the interview

Good oral and written proficiency in English

Good written and oral communication skills

Ability to work well in a team

Type of employment
Limit of tenure, four years according to HF 5 kap 7§.