Lund University, Faculty of Science, Department of Clinical Sciences, division of Radiation Physics

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 47 000 students and more than 8 800 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

The department of Medical Radiation Physics is engaged in research and education in ionizing and non-ionizing radiation, and its use mainly in medical applications. The major areas are magnetic resonance imaging (MRI), radiation therapy, X-ray physics, and nuclear medicine.

The MR physics research group (www.med.lu.se/klinvetlund/MR_physics), situated in the expanding Öresund region in southern Sweden, is active in the field of medical magnetic resonance, and has its primary focus on development of new techniques for assessment of functional information related to perfusion, diffusion, cortical activation/fMRI and flow. Emerging areas in the group encompass high field-studies using CEST as well as quantitative MRI in the brain and in the musculoskeletal system.

We now are searching for a project assistant.

Description

We intend to use natural sugar (D-glucose) as a biodegradable agent for diagnosing cancer with MRI. D-glucose is a regulatory approved biocompatible substance that is already used in glucose tolerance testing of diabetics in the clinic. Injection of small amounts of glucose will not change conventional MRI contrast. However, we will accomplish detection using a novel approach called CEST (chemical exchange saturation transfer) MRI. Using CEST, the presence of small (millimolar) amounts of glucose can be detected with greatly enhanced sensitivity through the water signal by using its hydroxyl protons as a natural label that exchanges with water protons.

Job Assignment

The main assignment is to develop and apply the glucose CEST (“glucoCEST”) method in healthy volunteers and in patients with brain cancer. More specifically, the tasks are to optimize imaging parameters and to implement post-processing methods and to develop methods for tracer-kinetic analysis of glucoCEST data.  Another CEST method that may be part of the project is Amide Proton Transfer (APT).

Eligibility

To be eligible you need a Master Degree in Medical Physics or a Master Degree in Medical Radiation physics

Evaluation criteria: 

  • Very good knowledge of MR physics
  • Completed degree project aimed at CEST or/and MRS and/or motion correction.
  • Documented good knowledge of MATLAB programming
  • Ability to cooperate with colleagues

Application

The application is to be made online. An incomplete application will not be processed.

The application must contain: 

  • 1 CV
  • 2 A copy of the 30 credit master's degree project thesis (or equivalent)
  • 3 Copies of certificates and documents that the applicant wishes to claim.
Type of employment Special fixed-term employment
Contract type Full time
First day of employment As soon as possible for 6 months
Salary Monthly salary
Number of positions 1
Full-time equivalent 100
City Lund
County Skåne län
Country Sweden
Reference number PA2019/428
Contact
  • Linda Knutsson, professor, +46 46 17 85 47
  • Magdalena Brossing, HR-coordinator, +46 46 222 9562
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-222 93 62
  • SACO:Saco-s-rådet vid Lunds universitet, 046-222 93 64
Published 05.Feb.2019
Last application date 15.Feb.2019 11:59 PM CET

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