Research Engineer in Mass Spectrometry-Based Proteomics - Hiring in process/Finished, not possible to apply

The research group

In the research group of Proteomic Hematology at the Division of Molecular Hematology, we conduct research to understand why leukemia in children behaves different from leukemia in adults. Our research is specifically focused on the role of proteins in blood cell development and leukemia. The research is important for finding new age-tailored therapeutic targets to treat this cancer specifically in children, and in adults. The group is led by Associate Senior Lecturer Jenny Hansson and the laboratory is located at the Biomedical Center in Lund. The research group is embedded in the Lund Stem Cell Center, a strategic center of excellence in life science, with a strong international position in the area of blood stem cell biology. Read more about our research here. 

Within the group and division we aim to maintain a good working environment that offers the conditions for development, work joy, and participation for all employees. The stimulating environment within the division as well as Lund Stem Cell Center also contributes to many collaborations and innovative thinking.

We are hereby seeking a highly motivated Research Engineer with a strong background in mass spectrometry-based proteomics to join us to answer complex biological questions in the areas of blood cell development, leukemia and stem cell biology. The position is a full time position time limited to 2 years with the proposed starting date February 1st 2022 or by agreement.

Work duties and area of expertise

The research engineer will design experiments, prepare samples for mass spectrometric analysis and apply advanced mass spectrometric approaches to stem cell research. The research engineer will have liberty to try a wide range of innovative approaches and is expected to implement and improve methods within especially cellular proteomics. Projects will include research questions relating to the research group (blood cell development and leukemia) as well as the rest of the Lund Stem Cell Center. The research engineer will be the driver of the projects initiated in the host research group, work in close collaboration with the other members of the research group and communicate with and report to collaboration partners within Lund Stem Cell Center. A substantial part of the work duties will include maintenance of an Exploris 480 (with FAIMSPro and Dionex Ultimate 3000 nLC) in coordination with the research group members.

The research engineer is expected to follow the development of mass spectrometry-based proteomics by frequent attendance to international conferences and workshops. Other common work duties and responsibilities within the research group may occur. We offer the opportunity to do cutting-edge research and be part of a stimulating scientific community within a world-renowned blood and stem cell research environment that fosters collaboration and innovative thinking.

Qualifications

The position requires:

• Master of Science in technical biology, analytical chemistry, molecular biology, biomedicine, cell biology, or similar.
• Good verbal and written communication skills in English
• A good sense of order in a research laboratory
• The applicant should be well experienced with mass spectrometry-based proteomics, including:

  - Practical experience with preparation of biological samples for mass spectrometric analysis

  - Good theoretical knowledge in advanced mass spectrometry

  - Experience with modern quantitative proteomic analysis

  - Basic knowledge in bioinformatics, with emphasis on analysis of proteomic data

Great emphasis will be placed on personal qualities. The applicant should be responsible, quality conscious, structured as well as have a willingness to learn new things. The applicant needs to have a good ability to work independently and take initiatives. The position also require you to have a good cooperative ability since the team members are working very closely together. 

Desired for the position is:

• PhD in proteomics
• Practical experience in trouble shooting, maintenance and service of LC and mass spectrometric equipment, especially Orbitrap MS
• Experience with analysis of post-translational modifications, especially phosphorylation and cysteine oxidation
• Experience with data independent acquisition
• Experience with topdown MS
• Familiarity with immunopeptidomic analysis
• Skills in programming and computational proteomics

Instructions for your application The application must contain a personal letter describing how you fulfill the desired qualifications, a CV and diploma.

Other The university applies individual salary setting. Please indicate your salary claim in your application.