BMA/Laboratory-/Research Engineer to the Center for Translational Genomics - Hiring in process/Finished, not possible to apply

The Research Group
The Center for Translational Genomics (CTG; https://www.ctg.lu.se/) is a prioritized research infrastructure at the Faculty of Medicine, Lund University, part of the Clinical Genomics platform at SciLifeLab (https://www.scilifelab.se/facilities/clinical-genomics/). The platform aims to offer translational and clinical researchers access to state-of-the-art methods in genomics (e.g. WGS, RNA-seq and new single cell analyses) and to quickly translate new research findings into improved clinical utility in close collaboration with the regional healthcare. Within CTG, there is great expertise in Next Generation Sequencing (NGS) technologies, bioinformatics and several different disease areas, and technologically, the unit is positioned at very forefront of the field with access to very powerful sequencing instruments (e.g.Illumina NovaSeq 6000). For data processing, the center uses a dedicated high-performance computing cluster at Lund University.

At the national level, CTG and Clinical Genomics Lund are also involved in a Swedish initiative for precision medicine; Genomic Medicine Sweden (https://genomicmedicine.se/), where the development of new methods for tomorrow's research and diagnostics is coordinated with the corresponding large-scale sequencing facilities at the country's other university hospitals. CTG currently has 12 employees and has recently moved to the newly formed research infrastructure center at BMC's D-building in Lund.

We are now looking for a driven, skilled, and service-oriented person, who wants to contribute to front-line research based on advanced genomics-based methods. 

Work duties and area of expertise
You will be part of a lab team of 5-6 people, in which you will primarily focus on services to research projects in need of different NGS-based methods. Protocols may originate from DNA or RNA from both human tissues and from microorganisms and may include WGS, RNA-sequencing, and more targeted applications (e.g. exome or gene panel sequencing).

The main tasks include:

• Project planning and execution - i.e. library preparation and sequencing - of established methods within CTG's standard genomics services (e.g. WGS or gene panel sequencing), with sequencing primarily performed on the Illumina platform (e.g. on the NovaSeq 6000).
• making project-specific cost calculations for service projects based on established templates
• Customer contact in connection with service projects
• Participating in laboratory development of new methods, e.g. for analysis of cell-free tumor DNA (ctDNA)
• Documenting and streamlining of laboratory workflows, e.g. writing protocols for new methods and participating in continuous improvement and automation of existing methods
• Various administrative tasks, e.g. ordering reagents and laboratory accessories

Qualifications
The position requires:

• Adequate University degree, e.g. bachelor's degree as a biomedical analyst or master's degree in molecular biology, biomedicine or equivalent
• At least 2 years of documented practical experience in molecular biology (e.g. extraction of DNA/RNA, PCR-based methods, Sanger sequencing, and/or NGS)
• Very good understanding of and/or previous practical experience in preparing NGS libraries
• Very good understanding of and/or previous practical experience of sequencing NGS libraries on the Illumina sequencing platform
• Excellent abilities to quickly learn new methods and establish new protocols
• Excellent oral and written communication skills in English

Great emphasis will be placed on personal suitability. The tasks require that you are structured and have an excellent ability to prioritize at work. The work is very team-based - both internally and externally - and therefore requires very good communication and collaboration skills. In addition, you need to have the ability to work independently. We are looking for you who are unpretentious and have a service-oriented approach.

The following are desired for the position:

• PhD in a relevant field (e.g. genomics or genetics)
• At least 2 years of practical experience of methods based on NGS (library preparation and/or sequencing)
• Experience in working with liquid handling systems for automation of laboratory protocols
• Experience in single cell sequencing methods (e.g. based on the 10X Genomics platform) and/or from tissue-based analysis
• Excellent oral and written communication skills in Swedish

Terms
The employment is a permanent full-time position with the desired start date of April 1, 2022, or according to agreement. Probationary employment of 6 months may be applied.

Instructions for your application
The application must contain a personal letter describing how you fulfill the desired qualifications, a CV and diploma.