Doctoral student within clinical genetics - Hiring in process/Finished, not possible to apply

Research group
The main focus of the research group is to increase our understanding of pathogenic mechanisms underlying acute leukemia development and how diagnostics and treatment of these disorders can be improved. The research group consists of about 10 employees with expert knowledge spanning from genomics and bioinformatics to advanced functional/mechanistic studies.
In recent years, the research group has had an increasing focus on large-scale analyzes of acute leukemias using genome-wide technologies, including different modalities of single cell sequencing. Work has also begun to combine the genomic analyzes with proteomic studies, a rapidly growing field of research called "proteogenomics". Within this project, the research group works closely with Professor Johan Malmström, Department of Clinical Sciences in Lund. In order to be able to analyze the large amounts of data generated and to find patterns of biological and/or clinical diagnostic significance, there is a need to be skilled in bioinformatics, machine learning and integrative analysis. Here you can read about our research.

Within the research group, we safeguard a workplace that is seen as developing and stimulating for all employees, and most of the projects are conducted in a team-based manner in which employees with different cutting-edge competencies are involved.

We are now looking for a doctoral student who will work with broad genomic and proteomic analyzes of acute leukemias in order to better understand why these disorders arise and to improve clinical diagnostics and treatment of patients diagnosed with these malignancies.

Work duties and areas of responsibility
In addition to compulsory courses for graduate students, the doctoral student will work on investigating acute myeloid leukemia using combined genomic and proteomic analyzes,  including different modalities of single cell analyzes. A large part of the work will include bioinformatics analyzes, the use of machine learning to identify proteogenomic patterns of biologic and/or diagnostic importance, and to work with integrative analysis of the data. Other existing tasks within the research group may also be relevant.

Qualifications
The following is required for the employment:

• A master's degree in Biomedical or Medical sciences.
• Documented experience of laboratory work in basic cell and molecular biology.
• Documented experience of bioinformatics analyzes of genomic data, especially in transcriptomic studies of acute leukemias and cancer
• Documented experience of working with R, Python and/or Bash.

Great emphasis will be placed on personal characteristics. The assignments require that you have the ability to work independently and the ability to collaborate well with others in the research group and researchers outside the subject area

The following is meritorious for the employment:

• Master's degree in bioinformatics or equivalent
• Very good knowledge in bioinformatics
• Very good knowledge of genetic changes in acute leukemias
• Good knowledge in machine learning

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

Assessment criteria
The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Only those admitted to third cycle studies may be appointed to a doctoral studentship. Doctoral studentships are regulated in the Higher Education Ordinance (1993:100),chapter 5,1-7 §§

Instructions for the application
The application must contain a personal letter describing how you fulfill the required qualifications, a CV and a diploma.