Lunds universitet, Medicinska fakulteten, Inst för laboratoriemedicin

Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has 40 000 students and 7 600 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malmö, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

The Department of Laboratory Medicine is one of six departments at Lund University’s Faculty of Medicine. We conduct leading research, both broad and specialised, within the field of laboratory medicine, focusing on the onset of disease and how we can improve diagnostics and treatment for patients. Some of our strongest areas with world-class research deal with cancer, genetics and blood.

The laboratory of RNA and Stem Cell Biology is embedded within the Lund Stem Cell Center, an internationally ranked research center within the strategic areas of Stem Cell Biology and Regenerative Medicine at Lund University, Scandinavia’s largest institution for education and research. Our research focuses on new post-transcriptional facets of gene expression control in stem and cancer cell at a molecular, cellular and organismal level. Specifically, we are interested in the molecular basis by which RNA modifications regulate gene expression in during development and in cancer.

Work duties:
Successful applicant will be directly responsible for the bioinformatics analysis of the main ongoing projects in the laboratory that center on the role of RNA modifying enzymes in stem and cancer cells. Specifically, the applicant is expected to apply different bioinformatics pipelines to: (1) characterize novel molecular signatures of small RNAs in human and murine hematopoietic cells; (2) unravel regulatory pathways governing the biogenesis of small RNAs target of RNA modifying enzymes in stem and cancer cells and; (3) study the effects of altered RNA modifications for splicing and translation genome-wide.

Other common lab related work duties are also included.  

Requierments:

  • The applicant must hold a PhD in Science within the field of Bioinformatics.
  • Applicants should have previous experience with analysis of a variety of high-throughput RNA sequencing (RNA-seq) datasets from mouse and human cells including whole transcriptome-seq, small RNA-seq, polysome-seq, ribosome footprint profile and iCLIP-seq.
  • In addition, good knowledge of pipelines for mRNA splicing analysis is required for this position.
  • The successful applicant is expected to work independently as well as part of a research team. Previous documented experience within academic groups interested in the research areas of RNA/cancer biology and hematology is needed.
  • Excellent verbal and written English communication skills are requested.

Desirable:

  • Previous experience with analysis of DNA and RNA epigenetics including ChIP-seq, ATAC-seq, mRIP-seq and pseudo-seq is highly preferred.
  • Successful applicants should possess the capacity to improve established models, protocols and/or develops new methods. 

Applicants’ personal suitability to work within our research environment will be considered.

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment 2019-09-04
Salary Monthly salary
Number of positions 1
Working hours 100
City Lund
County Skåne län
Country Sweden
Reference number PA2019/2664
Contact
  • Cristian Bellodi, +46462223054
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-222 93 62
  • SACO:Saco-s-rådet vid Lunds universitet, 046-222 93 64
  • SEKO: Seko Civil, 046-222 93 66
Published 05.Aug.2019
Last application date 18.Aug.2019 11:59 PM CET

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