Bioinformatician to the group RNA and Stem Cell Biology - Hiring in process/Finished, not possible to apply

The laboratory of RNA and Stem Cell Biology is embedded within the Lund Stem Cell Center, an internationally ranked research center within the strategic areas of Stem Cell Biology and Regenerative Medicine at Lund University, Scandinavia’s largest institution for education and research. Our research focuses on new post-transcriptional facets of gene expression control in stem and cancer cell at a molecular, cellular and organismal level. Specifically, we are interested in the molecular basis by which RNA modifications regulate gene expression in during development and in cancer.

Work duties:
Successful applicant will be directly responsible for the bioinformatics analysis of the main ongoing projects in the laboratory that center on the role of RNA modifying enzymes in stem and cancer cells. Specifically, the applicant is expected to apply different bioinformatics pipelines to: (1) characterize novel molecular signatures of small RNAs in human and murine hematopoietic cells; (2) unravel regulatory pathways governing the biogenesis of small RNAs target of RNA modifying enzymes in stem and cancer cells and; (3) study the effects of altered RNA modifications for splicing and translation genome-wide.

Other common lab related work duties are also included.  

Requierments:

• The applicant must hold a PhD in Science within the field of Bioinformatics.
• Applicants should have previous experience with analysis of a variety of high-throughput RNA sequencing (RNA-seq) datasets from mouse and human cells including whole transcriptome-seq, small RNA-seq, polysome-seq, ribosome footprint profile and iCLIP-seq.
• In addition, good knowledge of pipelines for mRNA splicing analysis is required for this position.
• The successful applicant is expected to work independently as well as part of a research team. Previous documented experience within academic groups interested in the research areas of RNA/cancer biology and hematology is needed.
• Excellent verbal and written English communication skills are requested.

Desirable:

• Previous experience with analysis of DNA and RNA epigenetics including ChIP-seq, ATAC-seq, mRIP-seq and pseudo-seq is highly preferred.
• Successful applicants should possess the capacity to improve established models, protocols and/or develops new methods. 

Applicants’ personal suitability to work within our research environment will be considered.